STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDZD8PDZ domain-containing protein 8. (1154 aa)    
Predicted Functional Partners:
RAB7A
RAB7A, member RAS oncogene family.
    
 
 0.762
ZFYVE27
Zinc finger FYVE-type containing 27.
    
 
 0.755
VAPB
Vesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
    
 
 0.705
GNG13
G protein subunit gamma 13.
     
  0.694
DESI1
Desumoylating isopeptidase 1.
      
 0.627
GRK3
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
  0.610
GRK2
G protein-coupled receptor kinase 2.
     
  0.610
UBQLNL
Ubiquitin-like domain-containing protein.
    
 
 0.595
STARD3
StAR related lipid transfer domain containing 3.
      
 0.594
BCAP31
B-cell receptor-associated protein 31 isoform b.
    
 
 0.583
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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