| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IFNAR1 | IFNGR1 | ENSSSCP00000067427 | ENSSSCP00000028797 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon gamma receptor 1. | 0.973 |
| IFNAR1 | IFNLR1 | ENSSSCP00000067427 | ENSSSCP00000060353 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interferon lambda receptor 1. | 0.931 |
| IFNAR1 | IL10RA | ENSSSCP00000067427 | ENSSSCP00000016008 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interleukin 10 receptor subunit alpha. | 0.668 |
| IFNAR1 | IL10RB | ENSSSCP00000067427 | ENSSSCP00000033998 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interleukin-10 receptor subunit beta. | 0.663 |
| IFNAR1 | IL22RA1 | ENSSSCP00000067427 | ENSSSCP00000047621 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Interleukin 22 receptor subunit alpha 1. | 0.591 |
| IFNAR1 | LOC110255217 | ENSSSCP00000067427 | ENSSSCP00000011416 | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | Uncharacterized protein. | 0.815 |
| IFNGR1 | IFNAR1 | ENSSSCP00000028797 | ENSSSCP00000067427 | Interferon gamma receptor 1. | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | 0.973 |
| IFNGR1 | IFNLR1 | ENSSSCP00000028797 | ENSSSCP00000060353 | Interferon gamma receptor 1. | Interferon lambda receptor 1. | 0.492 |
| IFNGR1 | IL10RA | ENSSSCP00000028797 | ENSSSCP00000016008 | Interferon gamma receptor 1. | Interleukin 10 receptor subunit alpha. | 0.468 |
| IFNGR1 | IL6R | ENSSSCP00000028797 | ENSSSCP00000068722 | Interferon gamma receptor 1. | Interleukin-6 receptor subunit alpha; Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis; Belongs to the type I cytokine receptor family. Type 3 subfamily. | 0.547 |
| IFNGR1 | LOC110255217 | ENSSSCP00000028797 | ENSSSCP00000011416 | Interferon gamma receptor 1. | Uncharacterized protein. | 0.754 |
| IFNLR1 | IFNAR1 | ENSSSCP00000060353 | ENSSSCP00000067427 | Interferon lambda receptor 1. | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | 0.931 |
| IFNLR1 | IFNGR1 | ENSSSCP00000060353 | ENSSSCP00000028797 | Interferon lambda receptor 1. | Interferon gamma receptor 1. | 0.492 |
| IFNLR1 | IL10RA | ENSSSCP00000060353 | ENSSSCP00000016008 | Interferon lambda receptor 1. | Interleukin 10 receptor subunit alpha. | 0.487 |
| IFNLR1 | IL10RB | ENSSSCP00000060353 | ENSSSCP00000033998 | Interferon lambda receptor 1. | Interleukin-10 receptor subunit beta. | 0.978 |
| IFNLR1 | IL22RA1 | ENSSSCP00000060353 | ENSSSCP00000047621 | Interferon lambda receptor 1. | Interleukin 22 receptor subunit alpha 1. | 0.586 |
| IFNLR1 | LOC110255217 | ENSSSCP00000060353 | ENSSSCP00000011416 | Interferon lambda receptor 1. | Uncharacterized protein. | 0.858 |
| IL10RA | IFNAR1 | ENSSSCP00000016008 | ENSSSCP00000067427 | Interleukin 10 receptor subunit alpha. | Interferon alpha/beta receptor 1; Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (By similarity). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). | 0.668 |
| IL10RA | IFNGR1 | ENSSSCP00000016008 | ENSSSCP00000028797 | Interleukin 10 receptor subunit alpha. | Interferon gamma receptor 1. | 0.468 |
| IL10RA | IFNLR1 | ENSSSCP00000016008 | ENSSSCP00000060353 | Interleukin 10 receptor subunit alpha. | Interferon lambda receptor 1. | 0.487 |