close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100517051Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family. (148 aa)    
Predicted Functional Partners:
LYZ
Lysozyme C-2; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
  
 
 
0.908
LTF
Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites.
      
 0.641
BPI
Bactericidal permeability increasing protein.
      
 0.610
PGLYRP1
20 kDa neutrophil cationic protein.
      
 0.582
PAEP
Beta-lactoglobulin-1A/1C; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
   
  
 0.577
VMO1
Uncharacterized protein.
      
 0.527
CSN2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
   
  
 0.514
SCNN1D
Amiloride-sensitive sodium channel subunit delta isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.512
CST8
Cystatin domain-containing protein.
   
  
 0.509
SLC35B4
Solute carrier family 35 member B4.
      
 0.503
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (34%) [HD]