Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTPAPPoly(A) RNA polymerase, mitochondrial. (598 aa)    
Predicted Functional Partners:
CALCOCO2
Calcium binding and coiled-coil domain 2.
    
 
 0.800
PAPOLG
Poly(A) polymerase gamma.
   
  
 0.750
GRSF1
G-rich RNA sequence binding factor 1.
    
 
 0.736
OSGEPL1
Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
      
 0.708
PDE12
2',5'-phosphodiesterase 12 isoform 1.
      
 0.705
FBXL12
F-box and leucine rich repeat protein 12.
      
 0.665
SLIRP
RRM domain-containing protein.
    
 
 0.661
YRDC
YrdC N6-threonylcarbamoyltransferase domain containing.
      
 0.658
PABPC5
Poly(A) binding protein cytoplasmic 5.
   
 
 0.643
MTSS2
MTSS I-BAR domain containing 2.
    
 
 0.641
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (16%) [HD]