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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSMEM2Leucine rich single-pass membrane protein 2. (158 aa)    
Predicted Functional Partners:
WDR47
WD repeat domain 47.
      
 0.730
LRRK1
Leucine rich repeat kinase 1.
      
 0.724
ARHGAP21
Rho GTPase activating protein 21.
      
 0.676
TFAP2B
Transcription factor AP-2 beta.
      
 0.666
UBAP2
Ubiquitin associated protein 2.
      
 0.611
AP3D1
Adaptor related protein complex 3 subunit delta 1.
      
 0.608
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
      
 0.600
SCUBE1
Signal peptide, CUB domain and EGF like domain containing 1.
      
 0.559
PDE1C
Phosphodiesterase.
      
 0.548
LIMK2
LIM domain kinase 2.
      
 0.545
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.