STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HYAL2Hyaluronidase. (476 aa)    
Predicted Functional Partners:
GUSB
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates.
   
 
 0.931
IDUA
Iduronidase alpha-L-.
    
 0.916
ARSB
Arylsulfatase B.
   
 
 0.909
CD44
CD44 molecule (Indian blood group).
   
 0.870
HAS1
Uncharacterized protein.
   
  
 0.733
HAS3
Hyaluronan synthase 3 isoform a.
   
  
 0.721
SHAS2
Uncharacterized protein.
   
  
 0.694
LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X2.
    
 0.671
HMMR
Hyaluronan mediated motility receptor.
   
 0.653
ACAN
Aggrecan core protein 2; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
   
 
 0.637
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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