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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD54L2RAD54 like 2. (1468 aa)    
Predicted Functional Partners:
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A.
    
 
 0.626
MDC1
Mediator of DNA damage checkpoint protein 1; Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be ac [...]
   
 
 0.578
SLF1
SMC5-SMC6 complex localization factor 1.
    
 
 0.576
DCLRE1B
5' exonuclease Apollo isoform a.
   
 
 0.547
GON4L
Myb-like domain-containing protein.
   
 
 0.545
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1.
      
 0.532
ZNF827
Zinc finger protein 827.
   
 
 0.527
FAM13B
Family with sequence similarity 13 member B.
      
 0.515
CXXC1
CXXC finger protein 1.
   
 
 0.511
FANCM
FA complementation group M.
    
 
 0.510
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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