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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2211 aa)    
Predicted Functional Partners:
CACNB1
Voltage-dependent L-type calcium channel subunit beta-1 isoform X1.
   
 0.959
CACNA2D2
Calcium voltage-gated channel auxiliary subunit alpha2delta 2.
   
 0.954
CALML5
Calmodulin like 5.
    
 0.946
CALM3
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.946
CACNB3
Voltage-dependent L-type calcium channel subunit beta-3 isoform 1.
   
 0.942
CALML4
Uncharacterized protein.
    
 0.927
KCNMB4
Potassium calcium-activated channel subfamily M regulatory beta subunit 4.
     
 0.925
HTR2C
5-hydroxytryptamine receptor 2C.
     
 0.922
CACNA1F
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
  
  
0.917
CACNA2D1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.917
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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