PTPRG protein (Sus scrofa) - STRING interaction network

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Score

PTPRG

Protein tyrosine phosphatase receptor type G. (1452 aa)

Predicted Functional Partners:

CNTN6

0.860

CNTN5

0.831

CSPG5

0.822

CNTN4

0.806

LUM

0.793

GRIN3A

0.769

IGSF10

0.767

CDK4

0.764

PAK1IP1

0.741

MCM7

0.722

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK4	MCM7	ENSSSCP00000022407	ENSSSCP00000050669	Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...]	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.623
CDK4	PTPRG	ENSSSCP00000022407	ENSSSCP00000012239	Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...]	Protein tyrosine phosphatase receptor type G.	0.764
CNTN4	PTPRG	ENSSSCP00000068362	ENSSSCP00000012239	Contactin 4.	Protein tyrosine phosphatase receptor type G.	0.806
CNTN5	PTPRG	ENSSSCP00000072383	ENSSSCP00000012239	Contactin 5.	Protein tyrosine phosphatase receptor type G.	0.831
CNTN6	PTPRG	ENSSSCP00000035069	ENSSSCP00000012239	Contactin 6.	Protein tyrosine phosphatase receptor type G.	0.860
CSPG5	PAK1IP1	ENSSSCP00000043854	ENSSSCP00000030936	Chondroitin sulfate proteoglycan 5.	PAK1 interacting protein 1.	0.869
CSPG5	PTPRG	ENSSSCP00000043854	ENSSSCP00000012239	Chondroitin sulfate proteoglycan 5.	Protein tyrosine phosphatase receptor type G.	0.822
GRIN3A	LUM	ENSSSCP00000058512	ENSSSCP00000000978	Glutamate ionotropic receptor NMDA type subunit 3A.	Lumican.	0.788
GRIN3A	MCM7	ENSSSCP00000058512	ENSSSCP00000050669	Glutamate ionotropic receptor NMDA type subunit 3A.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.787
GRIN3A	PTPRG	ENSSSCP00000058512	ENSSSCP00000012239	Glutamate ionotropic receptor NMDA type subunit 3A.	Protein tyrosine phosphatase receptor type G.	0.769
IGSF10	PTPRG	ENSSSCP00000038348	ENSSSCP00000012239	Immunoglobulin superfamily member 10.	Protein tyrosine phosphatase receptor type G.	0.767
LUM	GRIN3A	ENSSSCP00000000978	ENSSSCP00000058512	Lumican.	Glutamate ionotropic receptor NMDA type subunit 3A.	0.788
LUM	MCM7	ENSSSCP00000000978	ENSSSCP00000050669	Lumican.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.791
LUM	PTPRG	ENSSSCP00000000978	ENSSSCP00000012239	Lumican.	Protein tyrosine phosphatase receptor type G.	0.793
MCM7	CDK4	ENSSSCP00000050669	ENSSSCP00000022407	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...]	0.623
MCM7	GRIN3A	ENSSSCP00000050669	ENSSSCP00000058512	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Glutamate ionotropic receptor NMDA type subunit 3A.	0.787
MCM7	LUM	ENSSSCP00000050669	ENSSSCP00000000978	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Lumican.	0.791
MCM7	PTPRG	ENSSSCP00000050669	ENSSSCP00000012239	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Protein tyrosine phosphatase receptor type G.	0.722
PAK1IP1	CSPG5	ENSSSCP00000030936	ENSSSCP00000043854	PAK1 interacting protein 1.	Chondroitin sulfate proteoglycan 5.	0.869
PAK1IP1	PTPRG	ENSSSCP00000030936	ENSSSCP00000012239	PAK1 interacting protein 1.	Protein tyrosine phosphatase receptor type G.	0.741