Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE2Prickle planar cell polarity protein 2. (901 aa)    
Predicted Functional Partners:
VANGL1
Vang-like protein.
    
 0.995
VANGL2
Vang-like protein.
    
 0.985
DVL1
Dishevelled segment polarity protein 1.
    
 0.971
DVL2
Dishevelled segment polarity protein 2.
    
 0.969
DVL3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.960
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.890
PRICKLE4
Uncharacterized protein.
    
 0.883
INVS
Inversin.
   
 
 0.819
PRICKLE3
Prickle planar cell polarity protein 3.
     
  0.782
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.753
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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