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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRPF1Uncharacterized protein. (1214 aa)    
Predicted Functional Partners:
MEAF6
MYST/Esa1 associated factor 6.
    
 0.885
ING5
Inhibitor of growth family member 5.
    
 0.882
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.852
KAT6A
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.852
BRPF3
Bromodomain and PHD finger containing 3.
  
0.699
A0A286ZRB3_PIG
Histone domain-containing protein.
    
 0.692
ING4
Inhibitor of growth family member 4.
    
 0.684
COPG1
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
      
 0.669
DISP1
Dispatched RND transporter family member 1.
   
  
 0.661
KAT7
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 
 0.654
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.