STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRELD1Cysteine rich with EGF like domains 1. (419 aa)    
Predicted Functional Partners:
PRR9
Proline rich 9.
      
 0.611
AGGF1
Uncharacterized protein.
      
 0.560
PSMC5
26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...]
   
  
 0.547
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
      
 0.546
LMAN1
Lectin, mannose binding 1.
      
 0.532
SEPTIN3
Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
   
  
 0.511
VPS13A
Vacuolar protein sorting 13 homolog A.
      
 0.510
PARP8
Poly [ADP-ribose] polymerase.
      
 0.509
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif 16.
      
 0.509
NRBF2
Nuclear receptor binding factor 2.
      
 0.509
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.