STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (103 aa)    
Predicted Functional Partners:
NCKAP1
NCK associated protein 1.
    
 0.991
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.990
NCKAP1L
NCK associated protein 1 like.
    
 0.983
ABI2
Abl interactor 2.
    
 0.974
WASF2
Wiskott-Aldrich syndrome protein family member 2 isoform 2.
    
 0.969
WASF1
WH2 domain-containing protein.
    
 0.962
ABI1
Abl interactor 1 isoform b.
    
 0.957
ARPC3
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.954
ARPC4
Actin related protein 2/3 complex subunit 4.
   
 
 0.953
WASF3
Wiskott-Aldrich syndrome protein family member 3 isoform X1.
    
 0.945
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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