GATA2 protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

GATA2

GATA binding protein 2. (502 aa)

Predicted Functional Partners:

LMO2

0.868

TAL1

0.865

RUNX1

0.834

LDB1

0.791

ZFPM1

0.789

TCF12

0.667

CEBPB

0.658

ZFPM2

0.655

FOXC2

0.653

GFI1

0.626

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPB	GATA2	ENSSSCP00000045801	ENSSSCP00000012381	CCAAT/enhancer-binding protein.	GATA binding protein 2.	0.658
CEBPB	RUNX1	ENSSSCP00000045801	ENSSSCP00000041677	CCAAT/enhancer-binding protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.686
FOXC2	GATA2	ENSSSCP00000042729	ENSSSCP00000012381	Forkhead box C2.	GATA binding protein 2.	0.653
GATA2	CEBPB	ENSSSCP00000012381	ENSSSCP00000045801	GATA binding protein 2.	CCAAT/enhancer-binding protein.	0.658
GATA2	FOXC2	ENSSSCP00000012381	ENSSSCP00000042729	GATA binding protein 2.	Forkhead box C2.	0.653
GATA2	GFI1	ENSSSCP00000012381	ENSSSCP00000007358	GATA binding protein 2.	Growth factor independent 1 transcriptional repressor.	0.626
GATA2	LDB1	ENSSSCP00000012381	ENSSSCP00000011265	GATA binding protein 2.	LID domain-containing protein.	0.791
GATA2	LMO2	ENSSSCP00000012381	ENSSSCP00000014139	GATA binding protein 2.	LIM domain only 2.	0.868
GATA2	RUNX1	ENSSSCP00000012381	ENSSSCP00000041677	GATA binding protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.834
GATA2	TAL1	ENSSSCP00000012381	ENSSSCP00000036253	GATA binding protein 2.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.865
GATA2	TCF12	ENSSSCP00000012381	ENSSSCP00000050607	GATA binding protein 2.	Transcription factor 12 isoform a.	0.667
GATA2	ZFPM1	ENSSSCP00000012381	ENSSSCP00000049549	GATA binding protein 2.	Zinc finger protein, FOG family member 1.	0.789
GATA2	ZFPM2	ENSSSCP00000012381	ENSSSCP00000006451	GATA binding protein 2.	Uncharacterized protein.	0.655
GFI1	GATA2	ENSSSCP00000007358	ENSSSCP00000012381	Growth factor independent 1 transcriptional repressor.	GATA binding protein 2.	0.626
GFI1	RUNX1	ENSSSCP00000007358	ENSSSCP00000041677	Growth factor independent 1 transcriptional repressor.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.635
LDB1	GATA2	ENSSSCP00000011265	ENSSSCP00000012381	LID domain-containing protein.	GATA binding protein 2.	0.791
LDB1	LMO2	ENSSSCP00000011265	ENSSSCP00000014139	LID domain-containing protein.	LIM domain only 2.	0.989
LDB1	RUNX1	ENSSSCP00000011265	ENSSSCP00000041677	LID domain-containing protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.661
LDB1	TAL1	ENSSSCP00000011265	ENSSSCP00000036253	LID domain-containing protein.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.984
LDB1	TCF12	ENSSSCP00000011265	ENSSSCP00000050607	LID domain-containing protein.	Transcription factor 12 isoform a.	0.720