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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM108Transmembrane protein 108. (575 aa)    
Predicted Functional Partners:
SYNDIG1L
Synapse differentiation inducing 1 like.
      
 0.652
WDR64
Uncharacterized protein.
      
 0.622
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
      
 0.617
EPB41L4A
Erythrocyte membrane protein band 4.1 like 4A.
      
 0.613
ZNF488
Zinc finger protein 488.
      
 0.613
VPS45
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.611
COPS7B
COP9 signalosome subunit 7B.
      
 0.611
PLCXD3
Phosphatidylinositol specific phospholipase C X domain containing 3.
      
 0.610
TBC1D16
TBC1 domain family member 16.
      
 0.609
PLCH1
Phosphoinositide phospholipase C.
      
 0.601
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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