Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZIC1Zinc finger protein ZIC 1. (447 aa)    
Predicted Functional Partners:
PAX6
Paired box 6.
   
 
 0.700
HOXC8
Homeobox C8.
    
 
 0.548
LHX5
LIM/homeobox protein Lhx5.
  
 0.531
BARHL1
BarH like homeobox 1.
   
 0.513
CIDEA
CIDE-N domain-containing protein.
      
 0.513
MACROD1
Uncharacterized protein.
    
 
 0.506
PAX3
Paired box protein Pax-3 isoform PAX3e.
   
 
 0.501
CELF6
Uncharacterized protein.
   
  
 0.491
TMEM26
Transmembrane protein 26.
      
 0.481
NEUROD1
Neurogenic differentiation factor.
    
 
 0.462
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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