STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSC22D2TSC22 domain family protein 2 isoform 1. (787 aa)    
Predicted Functional Partners:
NRBP1
Nuclear receptor binding protein 1.
    
 
 0.781
TBL2
Transducin beta like 2.
    
 
 0.705
MORF4L1
Mortality factor 4-like protein 1 isoform 2.
      
 0.665
STAC2
SH3 and cysteine rich domain 2.
      
 0.654
GKN2
BRICHOS domain-containing protein.
      
 0.648
EME1
Essential meiotic structure-specific endonuclease 1.
      
 0.647
UBE4A
U-box domain-containing protein.
      
 0.640
PIF1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]
      
 0.603
GNAZ
Guanine nucleotide-binding protein G(Z) subunit alpha isoform X1.
      
 0.602
EIF2B3
Eukaryotic translation initiation factor 2B subunit gamma.
      
 0.601
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.