TSC22D2 protein (Sus scrofa) - STRING interaction network

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TSC22D2

TSC22 domain family protein 2 isoform 1. (787 aa)

Predicted Functional Partners:

TSC22D1

0.967

NRBP1

0.957

TSC22D4

0.932

TSC22D3

0.900

FAM117B

0.764

TBL2

0.650

UBE4A

0.613

STAC2

0.577

MORF4L1

0.575

PIF1

0.541

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM117B	TSC22D1	ENSSSCP00000017073	ENSSSCP00000031608	Family with sequence similarity 117 member B.	TSC22 domain family protein 1 isoform X1.	0.563
FAM117B	TSC22D2	ENSSSCP00000017073	ENSSSCP00000012480	Family with sequence similarity 117 member B.	TSC22 domain family protein 2 isoform 1.	0.764
FAM117B	TSC22D3	ENSSSCP00000017073	ENSSSCP00000062162	Family with sequence similarity 117 member B.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.653
MORF4L1	PIF1	ENSSSCP00000001932	ENSSSCP00000038141	Mortality factor 4-like protein 1 isoform 2.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	0.639
MORF4L1	TBL2	ENSSSCP00000001932	ENSSSCP00000036247	Mortality factor 4-like protein 1 isoform 2.	Transducin beta like 2.	0.714
MORF4L1	TSC22D2	ENSSSCP00000001932	ENSSSCP00000012480	Mortality factor 4-like protein 1 isoform 2.	TSC22 domain family protein 2 isoform 1.	0.575
MORF4L1	UBE4A	ENSSSCP00000001932	ENSSSCP00000063165	Mortality factor 4-like protein 1 isoform 2.	U-box domain-containing protein.	0.630
NRBP1	TSC22D1	ENSSSCP00000020910	ENSSSCP00000031608	Nuclear receptor binding protein 1.	TSC22 domain family protein 1 isoform X1.	0.929
NRBP1	TSC22D2	ENSSSCP00000020910	ENSSSCP00000012480	Nuclear receptor binding protein 1.	TSC22 domain family protein 2 isoform 1.	0.957
NRBP1	TSC22D3	ENSSSCP00000020910	ENSSSCP00000062162	Nuclear receptor binding protein 1.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.929
NRBP1	TSC22D4	ENSSSCP00000020910	ENSSSCP00000064554	Nuclear receptor binding protein 1.	TSC22 domain family member 4.	0.938
PIF1	MORF4L1	ENSSSCP00000038141	ENSSSCP00000001932	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	Mortality factor 4-like protein 1 isoform 2.	0.639
PIF1	TBL2	ENSSSCP00000038141	ENSSSCP00000036247	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	Transducin beta like 2.	0.727
PIF1	TSC22D2	ENSSSCP00000038141	ENSSSCP00000012480	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	TSC22 domain family protein 2 isoform 1.	0.541
PIF1	UBE4A	ENSSSCP00000038141	ENSSSCP00000063165	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	U-box domain-containing protein.	0.736
STAC2	TSC22D2	ENSSSCP00000071305	ENSSSCP00000012480	SH3 and cysteine rich domain 2.	TSC22 domain family protein 2 isoform 1.	0.577
TBL2	MORF4L1	ENSSSCP00000036247	ENSSSCP00000001932	Transducin beta like 2.	Mortality factor 4-like protein 1 isoform 2.	0.714
TBL2	PIF1	ENSSSCP00000036247	ENSSSCP00000038141	Transducin beta like 2.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]	0.727
TBL2	TSC22D2	ENSSSCP00000036247	ENSSSCP00000012480	Transducin beta like 2.	TSC22 domain family protein 2 isoform 1.	0.650
TBL2	UBE4A	ENSSSCP00000036247	ENSSSCP00000063165	Transducin beta like 2.	U-box domain-containing protein.	0.721