BCL6 protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

BCL6

B-cell lymphoma 6 protein isoform X1. (706 aa)

Predicted Functional Partners:

ICOS

0.959

IRF4

0.954

NCOR2

0.952

CXCR5

0.933

AICDA

0.929

PAX5

0.889

IL21R

0.880

FOXP3

0.849

CD40LG

0.826

CD44

0.822

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AICDA	BCL6	ENSSSCP00000068031	ENSSSCP00000012581	Activation induced cytidine deaminase.	B-cell lymphoma 6 protein isoform X1.	0.929
AICDA	CD40LG	ENSSSCP00000068031	ENSSSCP00000020229	Activation induced cytidine deaminase.	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	0.744
AICDA	CD44	ENSSSCP00000068031	ENSSSCP00000014130	Activation induced cytidine deaminase.	CD44 molecule (Indian blood group).	0.457
AICDA	CXCR5	ENSSSCP00000068031	ENSSSCP00000016021	Activation induced cytidine deaminase.	C-X-C chemokine receptor type 5 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.598
AICDA	ICOS	ENSSSCP00000068031	ENSSSCP00000028023	Activation induced cytidine deaminase.	IGv domain-containing protein.	0.415
AICDA	IL21R	ENSSSCP00000068031	ENSSSCP00000008345	Activation induced cytidine deaminase.	Interleukin 21 receptor.	0.649
AICDA	IRF4	ENSSSCP00000068031	ENSSSCP00000039925	Activation induced cytidine deaminase.	Interferon regulatory factor 4.	0.853
AICDA	PAX5	ENSSSCP00000068031	ENSSSCP00000039851	Activation induced cytidine deaminase.	Paired box 5.	0.820
BCL6	AICDA	ENSSSCP00000012581	ENSSSCP00000068031	B-cell lymphoma 6 protein isoform X1.	Activation induced cytidine deaminase.	0.929
BCL6	CD40LG	ENSSSCP00000012581	ENSSSCP00000020229	B-cell lymphoma 6 protein isoform X1.	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	0.826
BCL6	CD44	ENSSSCP00000012581	ENSSSCP00000014130	B-cell lymphoma 6 protein isoform X1.	CD44 molecule (Indian blood group).	0.822
BCL6	CXCR5	ENSSSCP00000012581	ENSSSCP00000016021	B-cell lymphoma 6 protein isoform X1.	C-X-C chemokine receptor type 5 isoform 1; Belongs to the G-protein coupled receptor 1 family.	0.933
BCL6	FOXP3	ENSSSCP00000012581	ENSSSCP00000049858	B-cell lymphoma 6 protein isoform X1.	Forkhead box protein P3 isoform a.	0.849
BCL6	ICOS	ENSSSCP00000012581	ENSSSCP00000028023	B-cell lymphoma 6 protein isoform X1.	IGv domain-containing protein.	0.959
BCL6	IL21R	ENSSSCP00000012581	ENSSSCP00000008345	B-cell lymphoma 6 protein isoform X1.	Interleukin 21 receptor.	0.880
BCL6	IRF4	ENSSSCP00000012581	ENSSSCP00000039925	B-cell lymphoma 6 protein isoform X1.	Interferon regulatory factor 4.	0.954
BCL6	NCOR2	ENSSSCP00000012581	ENSSSCP00000010425	B-cell lymphoma 6 protein isoform X1.	Uncharacterized protein.	0.952
BCL6	PAX5	ENSSSCP00000012581	ENSSSCP00000039851	B-cell lymphoma 6 protein isoform X1.	Paired box 5.	0.889
CD40LG	AICDA	ENSSSCP00000020229	ENSSSCP00000068031	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	Activation induced cytidine deaminase.	0.744
CD40LG	BCL6	ENSSSCP00000020229	ENSSSCP00000012581	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]	B-cell lymphoma 6 protein isoform X1.	0.826