ATP13A4 protein (Sus scrofa) - STRING interaction network

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Score

ATP13A4

Uncharacterized protein. (212 aa)

Predicted Functional Partners:

SLC8B1

0.794

SLC24A1

0.741

SLC8A1

0.640

TPCN1

0.580

GAK

0.556

ATP2B1

0.544

DNAJC6

0.438

CASR

0.426

TPCN2

0.420

H6PD

0.418

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP13A4	ATP2B1	ENSSSCP00000012592	ENSSSCP00000038808	Uncharacterized protein.	Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...]	0.544
ATP13A4	CASR	ENSSSCP00000012592	ENSSSCP00000041077	Uncharacterized protein.	Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...]	0.426
ATP13A4	DNAJC6	ENSSSCP00000012592	ENSSSCP00000035340	Uncharacterized protein.	DnaJ heat shock protein family (Hsp40) member C6.	0.438
ATP13A4	GAK	ENSSSCP00000012592	ENSSSCP00000026316	Uncharacterized protein.	Cyclin G associated kinase.	0.556
ATP13A4	H6PD	ENSSSCP00000012592	ENSSSCP00000064968	Uncharacterized protein.	Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.	0.418
ATP13A4	SLC24A1	ENSSSCP00000012592	ENSSSCP00000044173	Uncharacterized protein.	Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.741
ATP13A4	SLC8A1	ENSSSCP00000012592	ENSSSCP00000057989	Uncharacterized protein.	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.640
ATP13A4	SLC8B1	ENSSSCP00000012592	ENSSSCP00000010546	Uncharacterized protein.	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.794
ATP13A4	TPCN1	ENSSSCP00000012592	ENSSSCP00000056119	Uncharacterized protein.	Two pore calcium channel protein 1 isoform X1.	0.580
ATP13A4	TPCN2	ENSSSCP00000012592	ENSSSCP00000069704	Uncharacterized protein.	Uncharacterized protein.	0.420
ATP2B1	ATP13A4	ENSSSCP00000038808	ENSSSCP00000012592	Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...]	Uncharacterized protein.	0.544
ATP2B1	SLC8A1	ENSSSCP00000038808	ENSSSCP00000057989	Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...]	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.629
ATP2B1	SLC8B1	ENSSSCP00000038808	ENSSSCP00000010546	Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...]	Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.493
ATP2B1	TPCN1	ENSSSCP00000038808	ENSSSCP00000056119	Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-ind [...]	Two pore calcium channel protein 1 isoform X1.	0.414
CASR	ATP13A4	ENSSSCP00000041077	ENSSSCP00000012592	Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...]	Uncharacterized protein.	0.426
DNAJC6	ATP13A4	ENSSSCP00000035340	ENSSSCP00000012592	DnaJ heat shock protein family (Hsp40) member C6.	Uncharacterized protein.	0.438
DNAJC6	GAK	ENSSSCP00000035340	ENSSSCP00000026316	DnaJ heat shock protein family (Hsp40) member C6.	Cyclin G associated kinase.	0.741
GAK	ATP13A4	ENSSSCP00000026316	ENSSSCP00000012592	Cyclin G associated kinase.	Uncharacterized protein.	0.556
GAK	DNAJC6	ENSSSCP00000026316	ENSSSCP00000035340	Cyclin G associated kinase.	DnaJ heat shock protein family (Hsp40) member C6.	0.741
H6PD	ATP13A4	ENSSSCP00000064968	ENSSSCP00000012592	Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.	Uncharacterized protein.	0.418