Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PDIA5Protein disulfide isomerase family A member 5. (566 aa)    
Predicted Functional Partners:
GATD3A
Uncharacterized protein.
      
 0.773
SUOX
Sulfite oxidase, mitochondrial isoform X1.
    
 0.756
BLOC1S4
Biogenesis of lysosomal organelles complex 1 subunit 4.
      
 0.744
RNASET2
Ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. May play a role in cellular RNA catabolism. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity).
    
 
 0.711
ERP29
Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase.
   
 0.650
HSPA5
Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]
   
 
 0.617
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
 
    
 0.615
DNAJC3
Uncharacterized protein.
   
 0.611
B4GALT7
Uncharacterized protein.
      
 0.600
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.593
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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