Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PARP14Poly [ADP-ribose] polymerase. (1784 aa)    
Predicted Functional Partners:
IFIH1
Interferon induced with helicase C domain 1.
   
 
 0.789
PARP4
Poly [ADP-ribose] polymerase.
   
 
 0.787
PARP9
Poly(ADP-ribose) polymerase family member 9.
  
 
0.773
GIMAP8
GTPase, IMAP family member 8.
      
 0.763
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.747
PARP16
Poly [ADP-ribose] polymerase.
      
 0.720
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 
 0.692
PARP2
Poly [ADP-ribose] polymerase.
   
 
 0.664
PKM
Multifunctional fusion protein; Belongs to the pyruvate kinase family.
   
 
 0.663
DTX3L
Deltex E3 ubiquitin ligase 3L.
   
 
 0.658
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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