Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CPOXUncharacterized protein. (443 aa)    
Predicted Functional Partners:
UROD
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.993
PPOX
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.989
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
  
 0.950
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.911
ENDOV
Endonuclease V.
  
 0.905
UROS
Uroporphyrinogen III synthase.
     
 0.884
HMBS
Porphobilinogen deaminase isoform 1.
  
 
 0.812
TWNK
Twinkle protein, mitochondrial isoform A.
    
   0.770
SKIDA1
SKI/DACH domain containing 1.
    
   0.737
OGFOD1
2-oxoglutarate and iron dependent oxygenase domain containing 1.
   
  
 0.670
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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