STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS15Enteropeptidase non-catalytic heavy chain; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. (1049 aa)    
Predicted Functional Partners:
MUC1
SEA domain-containing protein.
   
 
 0.776
AGRN
Agrin.
   
 
 0.759
SLC5A1
Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
   
  
 0.646
SLC5A4
Solute carrier family 5 member 4; Has electrogenic activity in response to glucose, and may function as a glucose sensor. Also has low-affinity sodium/glucose cotransporter activity; sugar transport activity is tightly coupled to ion transport at neutral pH but is reduced under more acidic conditions. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.641
LOC102159834
Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.618
TBC1D31
TBC1 domain family member 31.
      
 0.611
PNLIP
Pancreatic triacylglycerol lipase.
   
 
 0.608
MUC13
Uncharacterized protein.
   
 
 0.602
MUC4
Uncharacterized protein.
   
 
 0.596
LOC100302368
Trypsin.
   
 
0.575
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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