Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGFL6EGF like domain multiple 6. (536 aa)    
Predicted Functional Partners:
TCEANC
Transcription elongation factor A N-terminal and central domain containing.
 
  
 0.833
GEMIN8
Gem nuclear organelle associated protein 8.
      
 0.688
DENND5B
DENN domain containing 5B.
      
 0.684
AJAP1
Adherens junctions associated protein 1.
      
 0.660
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.638
AKAP11
A-kinase anchoring protein 11.
      
 0.609
NDNF
Neuron derived neurotrophic factor.
      
 0.597
PNPLA4
PNPLA domain-containing protein.
      
 0.575
PNPLA4-2
Patatin like phospholipase domain containing 4.
      
 0.575
WDR90
WD repeat domain 90.
   
 0.571
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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