Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TCEANCTranscription elongation factor A N-terminal and central domain containing. (352 aa)    
Predicted Functional Partners:
GEMIN8
Gem nuclear organelle associated protein 8.
   
  
 0.908
EGFL6
EGF like domain multiple 6.
 
  
 0.833
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
 0.758
OBI1
RING finger protein 219 isoform X1.
    
   0.714
CTPS2
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
   
  
 0.699
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.661
POLR2E
RNA polymerase II subunit E.
   
 0.654
POLR2K
RNA polymerase II subunit K.
   
 0.644
POLR2F
RNA polymerase II subunit F.
   
 0.642
POLR2C
DNA-directed RNA polymerase II subunit RPB3.
   
 0.638
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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