node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGMAT | AOC1 | ENSSSCP00000062464 | ENSSSCP00000038000 | Agmatinase; Belongs to the arginase family. | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | 0.926 |
AGMAT | LOC100520618 | ENSSSCP00000062464 | ENSSSCP00000003903 | Agmatinase; Belongs to the arginase family. | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.971 |
AGMAT | ODC1 | ENSSSCP00000062464 | ENSSSCP00000071030 | Agmatinase; Belongs to the arginase family. | Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.976 |
AGMAT | PAOX | ENSSSCP00000062464 | ENSSSCP00000039465 | Agmatinase; Belongs to the arginase family. | Amino_oxidase domain-containing protein. | 0.463 |
AGMAT | SAT1 | ENSSSCP00000062464 | ENSSSCP00000012958 | Agmatinase; Belongs to the arginase family. | Diamine acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)- acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine (By similarity). | 0.923 |
AGMAT | SMOX | ENSSSCP00000062464 | ENSSSCP00000007602 | Agmatinase; Belongs to the arginase family. | Spermine oxidase. | 0.501 |
AGMAT | SRM | ENSSSCP00000062464 | ENSSSCP00000025944 | Agmatinase; Belongs to the arginase family. | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | 0.978 |
AOC1 | AGMAT | ENSSSCP00000038000 | ENSSSCP00000062464 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Agmatinase; Belongs to the arginase family. | 0.926 |
AOC1 | LOC100520618 | ENSSSCP00000038000 | ENSSSCP00000003903 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.914 |
AOC1 | MAOA | ENSSSCP00000038000 | ENSSSCP00000013044 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). | 0.960 |
AOC1 | MAOB | ENSSSCP00000038000 | ENSSSCP00000022462 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.960 |
AOC1 | ODC1 | ENSSSCP00000038000 | ENSSSCP00000071030 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.945 |
AOC1 | PAOX | ENSSSCP00000038000 | ENSSSCP00000039465 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Amino_oxidase domain-containing protein. | 0.635 |
AOC1 | SAT1 | ENSSSCP00000038000 | ENSSSCP00000012958 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Diamine acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)- acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine (By similarity). | 0.904 |
AOC1 | SRM | ENSSSCP00000038000 | ENSSSCP00000025944 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | 0.933 |
ELAC1 | SAT1 | ENSSSCP00000023166 | ENSSSCP00000012958 | Zinc phosphodiesterase ELAC protein 1. | Diamine acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)- acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine (By similarity). | 0.703 |
LOC100520618 | AGMAT | ENSSSCP00000003903 | ENSSSCP00000062464 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Agmatinase; Belongs to the arginase family. | 0.971 |
LOC100520618 | AOC1 | ENSSSCP00000003903 | ENSSSCP00000038000 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. | 0.914 |
LOC100520618 | ODC1 | ENSSSCP00000003903 | ENSSSCP00000071030 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.903 |
LOC100520618 | PAOX | ENSSSCP00000003903 | ENSSSCP00000039465 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Amino_oxidase domain-containing protein. | 0.685 |