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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFYZinc finger X-chromosomal protein; Probable transcriptional activator; Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. (798 aa)    
Predicted Functional Partners:
SRY
Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development. It is responsible for initiating male sex determination. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Promotes DNA bending (By similarity).
   
 
 0.873
LOC106504154
Sex-determining region Y protein; Transcriptional regulator that controls a genetic switch in male development; Belongs to the SRY family.
   
 
 0.858
KDM5D
Lysine demethylase 5D.
   
 
 0.843
LOC100624590
ATP-dependent RNA helicase DDX3X isoform 2; Belongs to the DEAD box helicase family.
   
 
 0.827
EIF1AY
Eukaryotic translation initiation factor 1A Y-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
   
  
 0.791
AMELY
Amelogenin; Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel; Belongs to the amelogenin family.
   
  
 0.756
LOC100625207
USP domain-containing protein; Belongs to the peptidase C19 family.
   
  
 0.679
RBMX
RNA binding motif protein X-linked.
    
 
 0.622
LOC102162178
USP domain-containing protein; Belongs to the peptidase C19 family.
   
  
 0.602
USP9X
Putative ubiquitin carboxyl-terminal hydrolase FAF-X isoform X4; Belongs to the peptidase C19 family.
   
  
 0.591
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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