STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQSEC2IQ motif and Sec7 domain 2. (1488 aa)    
Predicted Functional Partners:
BBOF1
Basal body orientation factor 1.
      
 0.850
GPR160
Putative G-protein coupled receptor 160 isoform X1.
      
 0.846
RPS6KA6
Ribosomal protein S6 kinase.
      
 0.840
COLGALT2
Procollagen galactosyltransferase 2 isoform 1precursor.
      
 0.761
VPS13A
Vacuolar protein sorting 13 homolog A.
      
 0.689
TNIK
TRAF2 and NCK-interacting protein kinase isoform 1.
    
 
 0.671
ARF6
ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (By similarity). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (By similarity). Plays an important role in membrane trafficking, during junctional remodeling and epithelial po [...]
    
 
 0.628
MYO1F
Myosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.610
PDLIM4
PDZ and LIM domain protein 4 isoform 1.
      
 0.608
HMCN1
Hemicentin-1.
      
 0.607
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.