CYLC1 protein (Sus scrofa) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

CYLC1

Cylicin 1. (650 aa)

Predicted Functional Partners:

RNF114

0.921

XRN2

0.731

RIBC1

0.727

DMRT1

0.690

QKI

0.670

DYNLT3

0.652

CCIN

0.645

BRWD3

0.611

APOOL

0.563

TENT5D

0.561

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOOL	BRWD3	ENSSSCP00000060242	ENSSSCP00000033042	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	Bromodomain and WD repeat domain containing 3.	0.596
APOOL	CYLC1	ENSSSCP00000060242	ENSSSCP00000013253	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	Cylicin 1.	0.563
APOOL	TENT5D	ENSSSCP00000060242	ENSSSCP00000013249	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	Terminal nucleotidyltransferase 5D.	0.582
BRWD3	APOOL	ENSSSCP00000033042	ENSSSCP00000060242	Bromodomain and WD repeat domain containing 3.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.596
BRWD3	CYLC1	ENSSSCP00000033042	ENSSSCP00000013253	Bromodomain and WD repeat domain containing 3.	Cylicin 1.	0.611
BRWD3	TENT5D	ENSSSCP00000033042	ENSSSCP00000013249	Bromodomain and WD repeat domain containing 3.	Terminal nucleotidyltransferase 5D.	0.581
CCIN	CYLC1	ENSSSCP00000005733	ENSSSCP00000013253	Calicin.	Cylicin 1.	0.645
CYLC1	APOOL	ENSSSCP00000013253	ENSSSCP00000060242	Cylicin 1.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.563
CYLC1	BRWD3	ENSSSCP00000013253	ENSSSCP00000033042	Cylicin 1.	Bromodomain and WD repeat domain containing 3.	0.611
CYLC1	CCIN	ENSSSCP00000013253	ENSSSCP00000005733	Cylicin 1.	Calicin.	0.645
CYLC1	DMRT1	ENSSSCP00000013253	ENSSSCP00000067348	Cylicin 1.	Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...]	0.690
CYLC1	DYNLT3	ENSSSCP00000013253	ENSSSCP00000027789	Cylicin 1.	Dynein light chain Tctex-type 3.	0.652
CYLC1	QKI	ENSSSCP00000013253	ENSSSCP00000051820	Cylicin 1.	Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).	0.670
CYLC1	RIBC1	ENSSSCP00000013253	ENSSSCP00000071388	Cylicin 1.	RIB43A domain with coiled-coils 1.	0.727
CYLC1	RNF114	ENSSSCP00000013253	ENSSSCP00000049061	Cylicin 1.	E3 ubiquitin-protein ligase RNF114; E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity. Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3. May promote the ubiquitination of TRAF6 as well. Acts also as a negative regulator of T-cell activation. Inhibits cellular dsRNA responses and interferon produ [...]	0.921
CYLC1	TENT5D	ENSSSCP00000013253	ENSSSCP00000013249	Cylicin 1.	Terminal nucleotidyltransferase 5D.	0.561
CYLC1	XRN2	ENSSSCP00000013253	ENSSSCP00000033620	Cylicin 1.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.731
DMRT1	CYLC1	ENSSSCP00000067348	ENSSSCP00000013253	Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...]	Cylicin 1.	0.690
DMRT1	RNF114	ENSSSCP00000067348	ENSSSCP00000049061	Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and prom [...]	E3 ubiquitin-protein ligase RNF114; E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity. Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3. May promote the ubiquitination of TRAF6 as well. Acts also as a negative regulator of T-cell activation. Inhibits cellular dsRNA responses and interferon produ [...]	0.670
DYNLT3	CYLC1	ENSSSCP00000027789	ENSSSCP00000013253	Dynein light chain Tctex-type 3.	Cylicin 1.	0.652