Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCDH19Protocadherin 19. (1145 aa)    
Predicted Functional Partners:
KCNQ2
Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family.
      
 0.699
FCGR1A
Uncharacterized protein.
    
   0.611
CENPI
Centromere protein I.
      
 0.600
CDKL5
Cyclin dependent kinase like 5.
      
 0.592
STXBP1
Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.564
UNC5B
Unc-5 netrin receptor B.
    
 
 0.557
SCN1A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.554
GPR155
G protein-coupled receptor 155.
      
 0.553
KCNC1
Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family.
      
 0.553
SPTAN1
Spectrin alpha, non-erythrocytic 1.
      
 0.536
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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