Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRPS1Uncharacterized protein. (319 aa)    
Predicted Functional Partners:
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
   
 0.950
PPAT
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.903
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
   
 0.861
RPIA
Ribose-5-phosphate isomerase; Belongs to the ribose 5-phosphate isomerase family.
  
 
 0.836
UMPS
Uridine monophosphate synthetase.
  
 
 0.817
RBKS
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.814
TKTL1
Transketolase-like protein 1.
   
 
 0.806
TKTL2
Transketolase like 2.
   
 
 0.806
TKT
Transketolase.
   
 
 0.806
PGM2
Phosphoglucomutase 2.
  
 0.788
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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