STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDSSulfatase domain-containing protein. (581 aa)    
Predicted Functional Partners:
IDUA
Iduronidase alpha-L-.
     
 0.974
HPSE
Heparanase isoform 1 preproprotein.
     
 0.902
HPSE2
Inactive heparanase-2 isoform 1.
     
 0.902
SUMF1
Sulfatase modifying factor 1.
  
 
 0.795
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
  
 
 
 0.679
NAGLU
N-acetyl-alpha-glucosaminidase.
 
 
  
 0.636
AGA
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase isoform 1 preproprotein.
   
  
 0.619
ARSA
Sulfatase domain-containing protein.
  
   
0.586
TFRC
Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).
   
  
 0.584
TPP1
Tripeptidyl-peptidase 1 preproprotein.
    
 
 0.557
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.