STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
RENBPN-acylglucosamine 2-epimerase; Catalyzes the interconversion of N-acetylglucosamine to N- acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway; Belongs to the N-acylglucosamine 2-epimerase family. (450 aa)    
Predicted Functional Partners:
NAGK
N-acetylglucosamine kinase.
     
 0.969
GNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform 1.
     
 0.935
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
      
 0.736
UAP1L1
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1.
   
  
 0.710
IQCF5
IQ motif containing F5.
      
 0.678
LRRC17
Leucine rich repeat containing 17.
      
 0.618
AVPR2
Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption (By similarity).
   
  
 0.616
ARFGAP3
ADP ribosylation factor GTPase activating protein 3.
    
 
 0.599
COPS9
Uncharacterized protein.
      
 0.574
KCNS1
Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family.
   
  
 0.553
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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