Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GAB3GRB2-associated-binding protein 3 isoform 2. (576 aa)    
Predicted Functional Partners:
SPAI-2
Sodium/potassium ATPase inhibitor SPAI-2; Inhibits Na(+),K(+) ATPase by the competitive mode against Na(+).
      
 0.876
GRB2
Growth factor receptor-bound protein 2 isoform 1.
    
 0.731
LYN
Tyrosine-protein kinase.
   
 0.669
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
      
 0.666
BCO1
Beta-carotene oxygenase 1.
      
 0.666
PI3
Elafin; Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis (By similarity).
      
 0.595
CELA2A
Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily.
      
 0.595
CRK
CRK proto-oncogene, adaptor protein.
      
 0.559
BABAM2
BRISC and BRCA1 A complex member 2.
      
 0.546
ARHGEF9
Uncharacterized protein.
      
 0.544
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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