STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEND1Cell cycle exit and neuronal differentiation protein 1; Involved in neuronal differentiation. (140 aa)    
Predicted Functional Partners:
SSH3
Slingshot protein phosphatase 3.
      
 0.849
AHI1
Abelson helper integration site 1.
      
 0.849
KLHL35
Kelch like family member 35.
      
 0.779
HAP1
Huntingtin associated protein 1.
      
 0.724
DLEU7
Deleted in lymphocytic leukemia 7.
      
 0.721
ADAM30
ADAM metallopeptidase domain 30.
      
 0.689
CYP2W1
Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family.
      
 0.670
DEGS2
Delta 4-desaturase, sphingolipid 2.
      
 0.667
CDH22
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.643
TOP1MT
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
      
 0.605
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.