RIN1 protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

Experiments

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[Homology]

Score

RIN1

Uncharacterized protein. (81 aa)

Predicted Functional Partners:

RRAS

0.900

RAB5A

0.900

RRAS2

0.900

NRAS

0.900

HRAS

0.900

ABL1

0.900

RAB5C

0.900

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	HRAS	ENSSSCP00000053721	ENSSSCP00000051149	Tyrosine-protein kinase.	HRas proto-oncogene, GTPase.	0.461
ABL1	NRAS	ENSSSCP00000053721	ENSSSCP00000046185	Tyrosine-protein kinase.	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.513
ABL1	RIN1	ENSSSCP00000053721	ENSSSCP00000013769	Tyrosine-protein kinase.	Uncharacterized protein.	0.900
HRAS	ABL1	ENSSSCP00000051149	ENSSSCP00000053721	HRas proto-oncogene, GTPase.	Tyrosine-protein kinase.	0.461
HRAS	NRAS	ENSSSCP00000051149	ENSSSCP00000046185	HRas proto-oncogene, GTPase.	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.917
HRAS	RIN1	ENSSSCP00000051149	ENSSSCP00000013769	HRas proto-oncogene, GTPase.	Uncharacterized protein.	0.900
HRAS	RRAS	ENSSSCP00000051149	ENSSSCP00000003452	HRas proto-oncogene, GTPase.	RAS related.	0.905
NRAS	ABL1	ENSSSCP00000046185	ENSSSCP00000053721	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	Tyrosine-protein kinase.	0.513
NRAS	HRAS	ENSSSCP00000046185	ENSSSCP00000051149	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	HRas proto-oncogene, GTPase.	0.917
NRAS	RIN1	ENSSSCP00000046185	ENSSSCP00000013769	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	Uncharacterized protein.	0.900
NRAS	RRAS	ENSSSCP00000046185	ENSSSCP00000003452	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	RAS related.	0.905
RAB5A	RAB5C	ENSSSCP00000034240	ENSSSCP00000072041	Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...]	Uncharacterized protein.	0.902
RAB5A	RIN1	ENSSSCP00000034240	ENSSSCP00000013769	Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...]	Uncharacterized protein.	0.900
RAB5C	RAB5A	ENSSSCP00000072041	ENSSSCP00000034240	Uncharacterized protein.	Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...]	0.902
RAB5C	RIN1	ENSSSCP00000072041	ENSSSCP00000013769	Uncharacterized protein.	Uncharacterized protein.	0.900
RIN1	ABL1	ENSSSCP00000013769	ENSSSCP00000053721	Uncharacterized protein.	Tyrosine-protein kinase.	0.900
RIN1	HRAS	ENSSSCP00000013769	ENSSSCP00000051149	Uncharacterized protein.	HRas proto-oncogene, GTPase.	0.900
RIN1	NRAS	ENSSSCP00000013769	ENSSSCP00000046185	Uncharacterized protein.	GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.	0.900
RIN1	RAB5A	ENSSSCP00000013769	ENSSSCP00000034240	Uncharacterized protein.	Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...]	0.900
RIN1	RAB5C	ENSSSCP00000013769	ENSSSCP00000072041	Uncharacterized protein.	Uncharacterized protein.	0.900