STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RELATranscription factor p65 isoform 1. (573 aa)    
Predicted Functional Partners:
RELB
RELB proto-oncogene, NF-kB subunit.
  
0.999
NFKBIA
NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
   
 0.998
NFKB1
Uncharacterized protein.
   
0.998
NFKBIB
NFKB inhibitor beta.
   
 0.991
CREBBP
CREB-binding protein isoform a.
    
 0.989
NFKB2
Nuclear factor NF-kappa-B p100 subunit isoform X1.
   
0.989
IKBKB
Inhibitor of kappa light chain gene enhancer in B cells, kinase beta.
   
 0.987
CHUK
Protein kinase domain-containing protein.
    
 0.987
KPNA4
Importin subunit alpha; Functions in nuclear protein import.
    
 0.980
NFKBIE
NFKB inhibitor epsilon.
   
 0.977
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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