PGA5 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PGA5

Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family. (385 aa)

Predicted Functional Partners:

F5

0.779

CTSH

0.643

NAPSA

0.614

CTSS

0.599

CSN3

0.599

GCNT7

0.553

LOC110258046

0.551

I3LLP2_PIG

0.551

LOC100153446

0.551

C6orf15

0.551

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C6orf15	GCNT7	ENSSSCP00000038798	ENSSSCP00000007989	Chromosome 6 open reading frame 15.	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; Glycosyltransferase.	0.846
C6orf15	PGA5	ENSSSCP00000038798	ENSSSCP00000013926	Chromosome 6 open reading frame 15.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.551
CSN3	PGA5	ENSSSCP00000009882	ENSSSCP00000013926	Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.599
CTSH	CTSS	ENSSSCP00000001934	ENSSSCP00000007089	Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family.	Cathepsin S; Belongs to the peptidase C1 family.	0.887
CTSH	NAPSA	ENSSSCP00000001934	ENSSSCP00000043222	Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family.	Napsin A aspartic peptidase; Belongs to the peptidase A1 family.	0.827
CTSH	PGA5	ENSSSCP00000001934	ENSSSCP00000013926	Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.643
CTSS	CTSH	ENSSSCP00000007089	ENSSSCP00000001934	Cathepsin S; Belongs to the peptidase C1 family.	Cathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family.	0.887
CTSS	NAPSA	ENSSSCP00000007089	ENSSSCP00000043222	Cathepsin S; Belongs to the peptidase C1 family.	Napsin A aspartic peptidase; Belongs to the peptidase A1 family.	0.564
CTSS	PGA5	ENSSSCP00000007089	ENSSSCP00000013926	Cathepsin S; Belongs to the peptidase C1 family.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.599
F5	PGA5	ENSSSCP00000006704	ENSSSCP00000013926	Coagulation factor V heavy chain; Coagulation factor V is a cofactor that participates with factor Xa to activate prothrombin to thrombin; Belongs to the multicopper oxidase family.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.779
GCNT7	C6orf15	ENSSSCP00000007989	ENSSSCP00000038798	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; Glycosyltransferase.	Chromosome 6 open reading frame 15.	0.846
GCNT7	PGA5	ENSSSCP00000007989	ENSSSCP00000013926	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; Glycosyltransferase.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.553
I3LLP2_PIG	LOC100153446	ENSSSCP00000025012	ENSSSCP00000026998	Alpha-amylase.	Alpha-amylase.	0.875
I3LLP2_PIG	LOC110258046	ENSSSCP00000025012	ENSSSCP00000023468	Alpha-amylase.	Alpha-amylase.	0.875
I3LLP2_PIG	PGA5	ENSSSCP00000025012	ENSSSCP00000013926	Alpha-amylase.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.551
LOC100153446	I3LLP2_PIG	ENSSSCP00000026998	ENSSSCP00000025012	Alpha-amylase.	Alpha-amylase.	0.875
LOC100153446	LOC110258046	ENSSSCP00000026998	ENSSSCP00000023468	Alpha-amylase.	Alpha-amylase.	0.875
LOC100153446	PGA5	ENSSSCP00000026998	ENSSSCP00000013926	Alpha-amylase.	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family.	0.551
LOC110258046	I3LLP2_PIG	ENSSSCP00000023468	ENSSSCP00000025012	Alpha-amylase.	Alpha-amylase.	0.875
LOC110258046	LOC100153446	ENSSSCP00000023468	ENSSSCP00000026998	Alpha-amylase.	Alpha-amylase.	0.875

page 1 of 2

Server load: low (20%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About