CBLIF protein (Sus scrofa) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

CBLIF

Cobalamin binding intrinsic factor. (425 aa)

Predicted Functional Partners:

CUBN

0.849

CD320

0.715

TCN1

0.642

AK5

0.633

PRSS8

0.613

VSIG2

0.608

IDUA

0.543

PGC

0.478

SPON2

0.473

CDO1

0.429

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK5	CBLIF	ENSSSCP00000074265	ENSSSCP00000013951	Adenylate kinase 5; Belongs to the adenylate kinase family.	Cobalamin binding intrinsic factor.	0.633
AK5	CDO1	ENSSSCP00000074265	ENSSSCP00000015125	Adenylate kinase 5; Belongs to the adenylate kinase family.	Cysteine dioxygenase.	0.447
CBLIF	AK5	ENSSSCP00000013951	ENSSSCP00000074265	Cobalamin binding intrinsic factor.	Adenylate kinase 5; Belongs to the adenylate kinase family.	0.633
CBLIF	CD320	ENSSSCP00000013951	ENSSSCP00000035786	Cobalamin binding intrinsic factor.	CD320 antigen isoform 1.	0.715
CBLIF	CDO1	ENSSSCP00000013951	ENSSSCP00000015125	Cobalamin binding intrinsic factor.	Cysteine dioxygenase.	0.429
CBLIF	CUBN	ENSSSCP00000013951	ENSSSCP00000011764	Cobalamin binding intrinsic factor.	Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...]	0.849
CBLIF	IDUA	ENSSSCP00000013951	ENSSSCP00000034841	Cobalamin binding intrinsic factor.	Iduronidase alpha-L-.	0.543
CBLIF	PGC	ENSSSCP00000013951	ENSSSCP00000033353	Cobalamin binding intrinsic factor.	Gastricsin; Hydrolyzes a variety of proteins.	0.478
CBLIF	PRSS8	ENSSSCP00000013951	ENSSSCP00000064982	Cobalamin binding intrinsic factor.	Serine protease 8; Belongs to the peptidase S1 family.	0.613
CBLIF	SPON2	ENSSSCP00000013951	ENSSSCP00000045991	Cobalamin binding intrinsic factor.	Spondin-2.	0.473
CBLIF	TCN1	ENSSSCP00000013951	ENSSSCP00000037395	Cobalamin binding intrinsic factor.	Transcobalamin-1; Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach (By similarity). Binds to cobalamin and to cobalamin analogs such as cobinamide; Belongs to the eukaryotic cobalamin transport proteins family.	0.642
CBLIF	VSIG2	ENSSSCP00000013951	ENSSSCP00000016121	Cobalamin binding intrinsic factor.	V-set and immunoglobulin domain containing 2.	0.608
CD320	CBLIF	ENSSSCP00000035786	ENSSSCP00000013951	CD320 antigen isoform 1.	Cobalamin binding intrinsic factor.	0.715
CD320	CUBN	ENSSSCP00000035786	ENSSSCP00000011764	CD320 antigen isoform 1.	Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...]	0.481
CDO1	AK5	ENSSSCP00000015125	ENSSSCP00000074265	Cysteine dioxygenase.	Adenylate kinase 5; Belongs to the adenylate kinase family.	0.447
CDO1	CBLIF	ENSSSCP00000015125	ENSSSCP00000013951	Cysteine dioxygenase.	Cobalamin binding intrinsic factor.	0.429
CUBN	CBLIF	ENSSSCP00000011764	ENSSSCP00000013951	Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...]	Cobalamin binding intrinsic factor.	0.849
CUBN	CD320	ENSSSCP00000011764	ENSSSCP00000035786	Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...]	CD320 antigen isoform 1.	0.481
CUBN	TCN1	ENSSSCP00000011764	ENSSSCP00000037395	Cubilin; Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal t [...]	Transcobalamin-1; Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach (By similarity). Binds to cobalamin and to cobalamin analogs such as cobinamide; Belongs to the eukaryotic cobalamin transport proteins family.	0.697
IDUA	CBLIF	ENSSSCP00000034841	ENSSSCP00000013951	Iduronidase alpha-L-.	Cobalamin binding intrinsic factor.	0.543