Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD44CD44 molecule (Indian blood group). (767 aa)    
Predicted Functional Partners:
ERBB2
Receptor protein-tyrosine kinase.
    
 0.990
NANOG
Homeobox domain-containing protein.
     
 0.983
SPP1
Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family.
   
 0.979
EGFR
Receptor protein-tyrosine kinase.
    
 0.969
COL1A1
Collagen type I alpha 1 chain.
    
 0.954
COL2A1
Collagen type II alpha 1 chain.
    
 0.951
TIAM1
T cell lymphoma invasion and metastasis 1.
    
 0.949
LAMA3
Laminin subunit alpha 3.
    
 0.948
CD34
CD34 molecule.
      
 0.943
ANK2
Uncharacterized protein.
   
 
 0.942
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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