STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SH2D3ASH2 domain containing 3A. (577 aa)    
Predicted Functional Partners:
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.858
EGFR
Receptor protein-tyrosine kinase.
    
   0.795
NEDD9
Neural precursor cell expressed, developmentally down-regulated 9.
    
 0.684
PRSS57
Serine protease 57; Belongs to the peptidase S1 family.
    
 
 0.646
NUP93
Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.
    
 
 0.568
KPNA1
IBB domain-containing protein.
    
 0.534
NUP85
Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC).
    
 
 0.466
ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
    
 0.458
KPNA3
Importin subunit alpha; Functions in nuclear protein import.
    
 0.451
CASS4
Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity).
    
 0.446
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.