| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANGPTL3 | ANGPTL4 | ENSSSCP00000004131 | ENSSSCP00000014452 | Fibrinogen C-terminal domain-containing protein. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.925 |
| ANGPTL3 | ANGPTL8 | ENSSSCP00000004131 | ENSSSCP00000038848 | Fibrinogen C-terminal domain-containing protein. | Angiopoietin-like protein 8. | 0.998 |
| ANGPTL3 | GPIHBP1 | ENSSSCP00000004131 | ENSSSCP00000036748 | Fibrinogen C-terminal domain-containing protein. | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | 0.926 |
| ANGPTL4 | ANGPTL3 | ENSSSCP00000014452 | ENSSSCP00000004131 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Fibrinogen C-terminal domain-containing protein. | 0.925 |
| ANGPTL4 | ANGPTL8 | ENSSSCP00000014452 | ENSSSCP00000038848 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Angiopoietin-like protein 8. | 0.984 |
| ANGPTL4 | CDH11 | ENSSSCP00000014452 | ENSSSCP00000029075 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | 0.904 |
| ANGPTL4 | CTNND1 | ENSSSCP00000014452 | ENSSSCP00000014004 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Catenin delta 1. | 0.800 |
| ANGPTL4 | GPIHBP1 | ENSSSCP00000014452 | ENSSSCP00000036748 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | 0.906 |
| ANGPTL4 | PDGFC | ENSSSCP00000014452 | ENSSSCP00000024797 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.702 |
| ANGPTL4 | PPARA | ENSSSCP00000014452 | ENSSSCP00000000007 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Uncharacterized protein. | 0.685 |
| ANGPTL4 | PPARG | ENSSSCP00000014452 | ENSSSCP00000012339 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.661 |
| ANGPTL4 | SERPINF1 | ENSSSCP00000014452 | ENSSSCP00000049229 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Serpin family F member 1; Belongs to the serpin family. | 0.632 |
| ANGPTL4 | TIMP1 | ENSSSCP00000014452 | ENSSSCP00000013066 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Metalloproteinase inhibitor 1; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity). | 0.608 |
| ANGPTL8 | ANGPTL3 | ENSSSCP00000038848 | ENSSSCP00000004131 | Angiopoietin-like protein 8. | Fibrinogen C-terminal domain-containing protein. | 0.998 |
| ANGPTL8 | ANGPTL4 | ENSSSCP00000038848 | ENSSSCP00000014452 | Angiopoietin-like protein 8. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.984 |
| ANGPTL8 | GPIHBP1 | ENSSSCP00000038848 | ENSSSCP00000036748 | Angiopoietin-like protein 8. | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | 0.939 |
| CDH11 | ANGPTL4 | ENSSSCP00000029075 | ENSSSCP00000014452 | Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.904 |
| CDH11 | CTNND1 | ENSSSCP00000029075 | ENSSSCP00000014004 | Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | Catenin delta 1. | 0.911 |
| CTNND1 | ANGPTL4 | ENSSSCP00000014004 | ENSSSCP00000014452 | Catenin delta 1. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.800 |
| CTNND1 | CDH11 | ENSSSCP00000014004 | ENSSSCP00000029075 | Catenin delta 1. | Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | 0.911 |