STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNN1Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (297 aa)    
Predicted Functional Partners:
ACTG2
Actin, gamma 2, smooth muscle, enteric
   
 
 0.909
ACTA2
Actin, aortic smooth muscle; Sus scrofa actin, alpha 2, smooth muscle, aorta (ACTA2), mRNA; Belongs to the actin family
   
 
 0.859
MYH11
Myosin, heavy chain 11, smooth muscle; Muscle contraction
   
 
 0.794
SMTN
Uncharacterized protein; Smoothelin
   
 
 0.744
ACTA1
Actin, alpha skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family
   
 
 0.695
ENSSSCP00000020377
Uncharacterized protein
   
 
 0.688
GAS2
Growth arrest-specific protein 2; Growth arrest-specific 2
   
 
 0.688
ACTL6A
Actin-like protein 6a isoform x1; Actin-like 6A; Belongs to the actin family
   
 
 0.627
PLS3
Low quality protein: plastin-3; Plastin 3
   
 
 0.623
SPEF1
Sperm flagellar protein 1; Sus scrofa sperm flagellar 1 (SPEF1), mRNA
      
 0.605
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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