Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100520720Uncharacterized protein. (513 aa)    
Predicted Functional Partners:
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
   
  0.543
H2AFZ
Histone H2A; Belongs to the histone H2A family.
    
  0.525
CBX5
Chromobox protein homolog 5.
    
  0.523
LOC100521680
Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]
    
  0.517
HIST1H3E
Histone H3; Belongs to the histone H3 family.
    
  0.517
LOC100621389
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.513
TRIM28
Tripartite motif containing 28.
   
  0.512
LOC100155267
Histone domain-containing protein; Belongs to the histone H2B family.
    
  0.508
HIST1H2BD
Histone H2B; Belongs to the histone H2B family.
    
  0.508
H2BU1
Histone H2B; Belongs to the histone H2B family.
    
  0.508
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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