Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (261 aa)    
Predicted Functional Partners:
DAZL
Deleted in azoospermia-like protein.
    
 
 0.896
DND1
DND microRNA-mediated repression inhibitor 1.
    
 
 0.881
TFAP2C
Transcription factor AP-2 gamma (Activating enhancer binding protein 2 gamma).
   
 
 0.836
PRDM14
PR/SET domain 14.
    
 
 0.801
STRA8
Stimulated by retinoic acid 8.
      
 0.793
PRDM1
PR/SET domain 1.
      
 0.785
DDX4
Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...]
    
 
 0.739
SOX17
SRY-box transcription factor 17.
    
 
 0.734
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 
 0.717
LIN28A
Protein lin-28 homolog A.
   
  
 0.694
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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