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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (261 aa)    
Predicted Functional Partners:
PRDM14
PR/SET domain 14.
    
 
 0.880
DAZL
Deleted in azoospermia-like protein.
    
 
 0.810
TFAP2C
Transcription factor AP-2 gamma (Activating enhancer binding protein 2 gamma).
   
  
 0.800
PUM2
Pumilio RNA binding family member 2.
   
 
 0.754
DND1
DND microRNA-mediated repression inhibitor 1.
      
 0.746
PUM1
Pumilio RNA binding family member 1.
   
 
 0.745
STRA8
Stimulated by retinoic acid 8.
      
 0.694
DDX4
Probable ATP-dependent RNA helicase DDX4; ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycl [...]
    
 
 0.686
PRDM1
PR/SET domain 1.
      
 0.673
UTF1
Uncharacterized protein.
      
 0.660
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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