DNAJB1 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DNAJB1

J domain-containing protein. (339 aa)

Predicted Functional Partners:

HSPA4

0.948

DNAJC3

0.945

MAPKAPK5

0.905

HSPA6

0.905

HSPA8

0.903

DNAJA2

0.895

A0A287BQU9_PIG

0.894

HSPA5

0.892

HSPH1

0.863

HSPA14

0.859

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A287BQU9_PIG	DNAJA2	ENSSSCP00000058891	ENSSSCP00000003066	Uncharacterized protein.	DnaJ heat shock protein family (Hsp40) member A2.	0.907
A0A287BQU9_PIG	DNAJB1	ENSSSCP00000058891	ENSSSCP00000014656	Uncharacterized protein.	J domain-containing protein.	0.894
A0A287BQU9_PIG	DNAJC3	ENSSSCP00000058891	ENSSSCP00000021430	Uncharacterized protein.	Uncharacterized protein.	0.618
A0A287BQU9_PIG	HSPA14	ENSSSCP00000058891	ENSSSCP00000071129	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 14; Belongs to the heat shock protein 70 family.	0.548
A0A287BQU9_PIG	HSPA4	ENSSSCP00000058891	ENSSSCP00000052080	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 4.	0.984
A0A287BQU9_PIG	HSPA5	ENSSSCP00000058891	ENSSSCP00000055982	Uncharacterized protein.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.850
A0A287BQU9_PIG	HSPA6	ENSSSCP00000058891	ENSSSCP00000073047	Uncharacterized protein.	Heat shock 70 kDa protein 6; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.819
A0A287BQU9_PIG	HSPA8	ENSSSCP00000058891	ENSSSCP00000036002	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.961
A0A287BQU9_PIG	HSPH1	ENSSSCP00000058891	ENSSSCP00000065843	Uncharacterized protein.	Heat shock protein family H (Hsp110) member 1.	0.847
DNAJA2	A0A287BQU9_PIG	ENSSSCP00000003066	ENSSSCP00000058891	DnaJ heat shock protein family (Hsp40) member A2.	Uncharacterized protein.	0.907
DNAJA2	DNAJB1	ENSSSCP00000003066	ENSSSCP00000014656	DnaJ heat shock protein family (Hsp40) member A2.	J domain-containing protein.	0.895
DNAJA2	DNAJC3	ENSSSCP00000003066	ENSSSCP00000021430	DnaJ heat shock protein family (Hsp40) member A2.	Uncharacterized protein.	0.702
DNAJA2	HSPA14	ENSSSCP00000003066	ENSSSCP00000071129	DnaJ heat shock protein family (Hsp40) member A2.	Heat shock protein family A (Hsp70) member 14; Belongs to the heat shock protein 70 family.	0.844
DNAJA2	HSPA4	ENSSSCP00000003066	ENSSSCP00000052080	DnaJ heat shock protein family (Hsp40) member A2.	Heat shock protein family A (Hsp70) member 4.	0.803
DNAJA2	HSPA5	ENSSSCP00000003066	ENSSSCP00000055982	DnaJ heat shock protein family (Hsp40) member A2.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.843
DNAJA2	HSPA6	ENSSSCP00000003066	ENSSSCP00000073047	DnaJ heat shock protein family (Hsp40) member A2.	Heat shock 70 kDa protein 6; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.864
DNAJA2	HSPA8	ENSSSCP00000003066	ENSSSCP00000036002	DnaJ heat shock protein family (Hsp40) member A2.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.928
DNAJA2	HSPH1	ENSSSCP00000003066	ENSSSCP00000065843	DnaJ heat shock protein family (Hsp40) member A2.	Heat shock protein family H (Hsp110) member 1.	0.744
DNAJB1	A0A287BQU9_PIG	ENSSSCP00000014656	ENSSSCP00000058891	J domain-containing protein.	Uncharacterized protein.	0.894
DNAJB1	DNAJA2	ENSSSCP00000014656	ENSSSCP00000003066	J domain-containing protein.	DnaJ heat shock protein family (Hsp40) member A2.	0.895