Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
SYDE1Synapse defective Rho GTPase homolog 1. (735 aa)    
Predicted Functional Partners:
POLR2D
RNA polymerase II subunit D.
    
   0.784
ILVBL
IlvB acetolactate synthase like; Belongs to the TPP enzyme family.
      
 0.765
GCM1
Glial cells missing transcription factor 1.
      
 0.722
APBB1
Amyloid beta precursor protein binding family B member 1.
    
   0.713
EPHX3
Epoxide hydrolase 3.
      
 0.653
CRK
CRK proto-oncogene, adaptor protein.
      
 0.649
GEN1
GEN1 Holliday junction 5' flap endonuclease.
      
 0.598
ERC1
ELKS/RAB6-interacting/CAST family member 1.
    
 
 0.593
ERC2
ELKS/RAB6-interacting/CAST family member 2.
    
 
 0.593
POLR2I
DNA-directed RNA polymerase II subunit RPB9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity).
    
   0.569
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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