node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTA2 | ACTC1 | ENSSSCP00000011135 | ENSSSCP00000005172 | Actin alpha 2, smooth muscle. | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.590 |
ACTA2 | ACTG2 | ENSSSCP00000011135 | ENSSSCP00000055602 | Actin alpha 2, smooth muscle. | Actin gamma 2, smooth muscle. | 0.901 |
ACTA2 | MYH7 | ENSSSCP00000011135 | ENSSSCP00000070632 | Actin alpha 2, smooth muscle. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.894 |
ACTA2 | MYL1 | ENSSSCP00000011135 | ENSSSCP00000017116 | Actin alpha 2, smooth muscle. | Uncharacterized protein. | 0.512 |
ACTA2 | MYL12A | ENSSSCP00000011135 | ENSSSCP00000003998 | Actin alpha 2, smooth muscle. | Myosin regulatory light chain 12A isoform 2. | 0.789 |
ACTA2 | TPM2 | ENSSSCP00000011135 | ENSSSCP00000041804 | Actin alpha 2, smooth muscle. | Uncharacterized protein; Belongs to the tropomyosin family. | 0.827 |
ACTA2 | TPM4 | ENSSSCP00000011135 | ENSSSCP00000040331 | Actin alpha 2, smooth muscle. | Tropomyosin alpha-4 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. | 0.800 |
ACTC1 | ACTA2 | ENSSSCP00000005172 | ENSSSCP00000011135 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Actin alpha 2, smooth muscle. | 0.590 |
ACTC1 | ACTG2 | ENSSSCP00000005172 | ENSSSCP00000055602 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Actin gamma 2, smooth muscle. | 0.589 |
ACTC1 | MYH7 | ENSSSCP00000005172 | ENSSSCP00000070632 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.999 |
ACTC1 | MYL1 | ENSSSCP00000005172 | ENSSSCP00000017116 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Uncharacterized protein. | 0.830 |
ACTC1 | MYL12A | ENSSSCP00000005172 | ENSSSCP00000003998 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin regulatory light chain 12A isoform 2. | 0.622 |
ACTC1 | TNNI3 | ENSSSCP00000005172 | ENSSSCP00000064102 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin I3, cardiac type. | 0.680 |
ACTC1 | TNNT2 | ENSSSCP00000005172 | ENSSSCP00000026957 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Uncharacterized protein. | 0.972 |
ACTC1 | TNNT3 | ENSSSCP00000005172 | ENSSSCP00000050941 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.547 |
ACTC1 | TPM2 | ENSSSCP00000005172 | ENSSSCP00000041804 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Uncharacterized protein; Belongs to the tropomyosin family. | 0.976 |
ACTC1 | TPM4 | ENSSSCP00000005172 | ENSSSCP00000040331 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Tropomyosin alpha-4 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. | 0.967 |
ACTG2 | ACTA2 | ENSSSCP00000055602 | ENSSSCP00000011135 | Actin gamma 2, smooth muscle. | Actin alpha 2, smooth muscle. | 0.901 |
ACTG2 | ACTC1 | ENSSSCP00000055602 | ENSSSCP00000005172 | Actin gamma 2, smooth muscle. | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.589 |
ACTG2 | MYH7 | ENSSSCP00000055602 | ENSSSCP00000070632 | Actin gamma 2, smooth muscle. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.879 |