HSH2D protein (Sus scrofa) - STRING interaction network

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HSH2D

Hematopoietic SH2 domain-containing protein isoform 1. (359 aa)

Predicted Functional Partners:

LOC100511937

0.720

CDC42

0.678

PIK3R1

0.665

PIK3R2

0.665

TNK2

0.649

PIK3CD

0.628

PIK3CB

0.628

PIK3CA

0.628

EPB41L4B

0.608

PPP2R2C

0.608

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	HSH2D	ENSSSCP00000029815	ENSSSCP00000014727	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Hematopoietic SH2 domain-containing protein isoform 1.	0.678
CDC42	LOC100511937	ENSSSCP00000029815	ENSSSCP00000053353	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein.	0.976
CDC42	PIK3CA	ENSSSCP00000029815	ENSSSCP00000052984	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.987
CDC42	PIK3CB	ENSSSCP00000029815	ENSSSCP00000052823	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.996
CDC42	PIK3CD	ENSSSCP00000029815	ENSSSCP00000003679	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.979
CDC42	PIK3R1	ENSSSCP00000029815	ENSSSCP00000024885	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Phosphoinositide-3-kinase regulatory subunit 1.	0.992
CDC42	PIK3R2	ENSSSCP00000029815	ENSSSCP00000060475	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Uncharacterized protein.	0.976
CDC42	TNK2	ENSSSCP00000029815	ENSSSCP00000023403	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.960
EPB41L4B	HSH2D	ENSSSCP00000005841	ENSSSCP00000014727	Erythrocyte membrane protein band 4.1 like 4B.	Hematopoietic SH2 domain-containing protein isoform 1.	0.608
HSH2D	CDC42	ENSSSCP00000014727	ENSSSCP00000029815	Hematopoietic SH2 domain-containing protein isoform 1.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.678
HSH2D	EPB41L4B	ENSSSCP00000014727	ENSSSCP00000005841	Hematopoietic SH2 domain-containing protein isoform 1.	Erythrocyte membrane protein band 4.1 like 4B.	0.608
HSH2D	LOC100511937	ENSSSCP00000014727	ENSSSCP00000053353	Hematopoietic SH2 domain-containing protein isoform 1.	Uncharacterized protein.	0.720
HSH2D	PIK3CA	ENSSSCP00000014727	ENSSSCP00000052984	Hematopoietic SH2 domain-containing protein isoform 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.628
HSH2D	PIK3CB	ENSSSCP00000014727	ENSSSCP00000052823	Hematopoietic SH2 domain-containing protein isoform 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.628
HSH2D	PIK3CD	ENSSSCP00000014727	ENSSSCP00000003679	Hematopoietic SH2 domain-containing protein isoform 1.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.628
HSH2D	PIK3R1	ENSSSCP00000014727	ENSSSCP00000024885	Hematopoietic SH2 domain-containing protein isoform 1.	Phosphoinositide-3-kinase regulatory subunit 1.	0.665
HSH2D	PIK3R2	ENSSSCP00000014727	ENSSSCP00000060475	Hematopoietic SH2 domain-containing protein isoform 1.	Uncharacterized protein.	0.665
HSH2D	PPP2R2C	ENSSSCP00000014727	ENSSSCP00000009286	Hematopoietic SH2 domain-containing protein isoform 1.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.608
HSH2D	TNK2	ENSSSCP00000014727	ENSSSCP00000023403	Hematopoietic SH2 domain-containing protein isoform 1.	Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.649
LOC100511937	CDC42	ENSSSCP00000053353	ENSSSCP00000029815	Uncharacterized protein.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.976