close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSH2DHematopoietic SH2 domain-containing protein isoform 1. (359 aa)    
Predicted Functional Partners:
GRAP
Uncharacterized protein.
   
  
 0.541
TXK
Tyrosine-protein kinase.
   
 
 0.523
SPAG5
Uncharacterized protein.
      
 0.518
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1.
      
 0.518
KIFC1
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.514
BCL7C
BAF chromatin remodeling complex subunit BCL7C.
      
 0.514
RECQL
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
  
 0.505
CACNA2D4
Calcium voltage-gated channel auxiliary subunit alpha2delta 4.
      
 0.501
CENPN
Centromere protein N.
      
 0.489
TMEM140
Transmembrane protein 140.
      
 0.487
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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