GRM6 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GRM6

Glutamate metabotropic receptor 6. (872 aa)

Predicted Functional Partners:

GNB3

0.951

GNAI1

0.935

GNG13

0.934

GNB2

0.933

GNB4

0.933

GNB5

0.930

GNA13

0.930

GNAI2

0.926

F2

0.922

GNAO1

0.922

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F2	GRM6	ENSSSCP00000014081	ENSSSCP00000014914	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Glutamate metabotropic receptor 6.	0.922
GNA13	GNAI1	ENSSSCP00000040165	ENSSSCP00000016334	G protein subunit alpha 13.	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	0.961
GNA13	GNAI2	ENSSSCP00000040165	ENSSSCP00000012152	G protein subunit alpha 13.	G protein subunit alpha i2.	0.961
GNA13	GNAO1	ENSSSCP00000040165	ENSSSCP00000040441	G protein subunit alpha 13.	Guanine nucleotide-binding protein G(O) subunit alpha isoform b.	0.950
GNA13	GNB2	ENSSSCP00000040165	ENSSSCP00000008190	G protein subunit alpha 13.	G protein subunit beta 2.	0.989
GNA13	GNB3	ENSSSCP00000040165	ENSSSCP00000000727	G protein subunit alpha 13.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.985
GNA13	GNB4	ENSSSCP00000040165	ENSSSCP00000036910	G protein subunit alpha 13.	G protein subunit beta 4.	0.991
GNA13	GNB5	ENSSSCP00000040165	ENSSSCP00000031679	G protein subunit alpha 13.	G protein subunit beta 5.	0.984
GNA13	GNG13	ENSSSCP00000040165	ENSSSCP00000008555	G protein subunit alpha 13.	G protein subunit gamma 13.	0.980
GNA13	GRM6	ENSSSCP00000040165	ENSSSCP00000014914	G protein subunit alpha 13.	Glutamate metabotropic receptor 6.	0.930
GNAI1	GNA13	ENSSSCP00000016334	ENSSSCP00000040165	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit alpha 13.	0.961
GNAI1	GNAI2	ENSSSCP00000016334	ENSSSCP00000012152	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit alpha i2.	0.991
GNAI1	GNAO1	ENSSSCP00000016334	ENSSSCP00000040441	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein G(O) subunit alpha isoform b.	0.981
GNAI1	GNB2	ENSSSCP00000016334	ENSSSCP00000008190	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit beta 2.	0.996
GNAI1	GNB3	ENSSSCP00000016334	ENSSSCP00000000727	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.995
GNAI1	GNB4	ENSSSCP00000016334	ENSSSCP00000036910	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit beta 4.	0.996
GNAI1	GNB5	ENSSSCP00000016334	ENSSSCP00000031679	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit beta 5.	0.995
GNAI1	GNG13	ENSSSCP00000016334	ENSSSCP00000008555	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit gamma 13.	0.993
GNAI1	GRM6	ENSSSCP00000016334	ENSSSCP00000014914	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Glutamate metabotropic receptor 6.	0.935
GNAI2	GNA13	ENSSSCP00000012152	ENSSSCP00000040165	G protein subunit alpha i2.	G protein subunit alpha 13.	0.961